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Description

PX-171-006: Phase Ib multicenter dose escalation study of carfilzomib (CFZ) plus lenalidomide (LEN) and low dose dexamethasone (loDex) in relapsed and refractory multiple myeloma (MM) -- Preliminary results

These results suggested that targeting GSR represents an effective strategy to perturb the redox balance, and GSR may be a potential therapeutic target for sorafenib-resistant HCC