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Key role of the cystine glutamate antiporter in cancer cells. (A) Download Scientific Diagram Doxorubicin and erastin co loaded hydroxyethyl starch polycaprolactone nanoparticles for synergistic cancer therapy ScienceDirect The ferroptosis inducer erastin irreversibly inhibits system xc and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells Scientific Reports Melatonin and erastin emerge synergistic anti tumor effects on oral squamous cell carcinoma by inducing apoptosis, ferroptosis, and inhibiting autophagy through promoting ROS Cellular & Molecular Biology Letters Springer Nature Link
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