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Intermittent and low-level inhibition of key UPS components, which triggered only very mild stress in the differentiating hMSCs, had surprisingly distinct effects on the bone-like material they formed, altering its stiffness and the amount of protein and crystalline mineral it contains, and affecting its micro- and ultra-structural organization (53)

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The number of cells determined by differential staining in blastocysts developing in groups to evaluate the effect of leonurine on blastocyst development is shown in Fig

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