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As a nutritional scientist, L-glutamine is one of the most common supplements I use when practicing clinical nutrition

Free naringenin, instead, exhibited a KP exponent ( n = 0.678) still corresponding to the anomalous region but with a higher release in the first hours, where dissolution and diffusion were minor due to low solubility properties of naringenin in the absence of structured vehicle systems

In particular, it migrates from neurons to astrocytes where as an agonist of the nuclear liver X receptors (LXRs), it influences the expression of target genes for cholesterol homeostasis and inflammatory responses and causes the efflux of ApoE-bound cholesterol from astrocytes

10.3389/fimmu.2020.00996 118 PrisacaruA