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749 These findings collectively indicate that the Nrf2/GSH/GPX4 axis could be a promising therapeutic target for cerebral I/R injury

MPA is rapidly metabolized to an inactive glucuronide conjugate by isoforms of the UDP -glucuronosyltransferases in the liver, kidney, and intestine [371,372]

Glutathione is required for essential body operations such as chemical and protein formation, tissue formation, and immune system support

The incidence and mortality rates of cardiovascular diseases are significantly higher in individuals with diabetes compared to non-diabetic individuals