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To test this hypothesis, an occupationally relevant dose of MDI (0.1% w/v) was reacted with varying concentrations of GSH (10 M-10 mM), and the reaction products were characterized with regard to mass/structure, and ability to carbamoylate human albumin, a major carrier protein for MDI in vivo

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It would be a disruption of the societal pact we have had since 1962 that drugs will be studied to see if they work before they are marketed in the U.S., said Janet Woodcock, a former FDA acting commissioner

METTL3-dependent N6-methyladenosine modification is involved in berberine-mediated neuroprotection in ischemic stroke by enhancing the stability of NEAT1 in astrocytes