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Thus, ferroptosis can be defined as a non-apoptotic mode of regulated cell death, driven by iron accumulation and membrane lipid peroxidation when GPX4 activity is inhibited (Fig

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The population of Cxcl2 + was characterized by the high expression of genes relevant to inflammation, fibrosis and lipid metabolism

Trends Cancer 8:190209 Nosalova N, Keselakova A, Kello M, Martinkova M, Fabianova D, Pilatova MB (2023) Involvement of both extrinsic and intrinsic apoptotic pathways in Tridecylpyrrolidine-Diol Derivative-Induced apoptosis in Vitro