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In a cohort of 163 patients with cirrhosis (of which 56 had ALD), gut microbiome antimicrobial resistance gene abundance was higher in patients with decompensated cirrhosis compared to compensated, and also associated with hospitalization and mortality

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Structural studies of retatrutide bound to GLP-1R, GIPR, and GCGR have been deposited in the Protein Data Bank, supporting docking, mutagenesis, and structure-activity work in computational pharmacology