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These findings are particularly noteworthy, as they not only elucidate the protective mechanisms of glutamine in myocardial infarction but also propose a potential biomarker for the early diagnosis and monitoring of CAD, which could transform the management of this widespread cardiovascular condition

Multiple studies have demonstrated that both pharmacological inhibition and genetic ablation of complex I can influence ferroptosis sensitivity in various disease contexts, including cancer, skin photoaging, Parkinsons disease and intracerebral hemorrhage 103,104,105,106

10.1038/onc.2009.79 Oncogene 50 JungH

Therefore, given that the solubility of LS-102 has been markedly improved compared to the precursor compound AS-IV, it can be employed as a novel synthetic drug containing carboxylic acid to treat metabolic diseases such as obesity through oral administration (21,215)