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Hereafter, 0.5 ml of non-clotted blood was transferred to a 2 ml vial and immediately centrifuged (3,000 g, 10 min), and the supernatant was subsequently removed

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Given the numerous examples of astrocyte dysfunction in ALS, targeting astrocytes and astrocyte replacement are promising therapeutic approaches that have shown positive results in fALS animal models (Table 1)