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AT dysfunction manifests when expansion limits are reached, forcing lipid accumulation in non-ATs and triggering systemic metabolic deterioration (37, 261)

Manipulations of Rac1 activity in the hippocampus using Rac1 inhibitor (NSC23766) and activator (CN04-A) were also reported to alter the maintenance of contextual fear memory in a similar fashion (Gan et al., 2016

Sci Rep 13(1):13 Cao CW et al (2022) Oral intake of chicken bone collagen peptides Anti-Skin aging in mice by regulating collagen degradation and Synthesis, inhibiting inflammation and activating lysosomes

Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro