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PMID 3301842

SunCHuangFLiuXXiaoXYangMHuGet al

SP-22 is a thioredoxin-dependent peroxide reductase in mitochondria

They are not specific and may include signs of left ventricle hypertrophy, low QRS voltage, nonspecific STT changes, and atrioventricular, supraventricular (mostly atrial fibrillation), or ventricular arrhythmias