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10.1186/s12929-021-00784-w 92 ImaiY.KubaK.RaoS.HuanY.GuoF.GuanB.et al (2005)

444 Many studies suggest that high glucose triggers increased mitochondrial fission in retinal capillaries, which induces cell death through the activation of pro-apoptotic genes and other methods, thereby triggering diabetic retinopathy