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Figure 1: Funding for SRH conditions in 2023, in USD millions Beyond size, the maturity of the R&D landscape for these conditions is also reflected in where investment is focused

It may also trigger other lytic cell death mechanisms, such as ferroptosis and pyroptosis, to increase the pathogenesis of intestinal diseases (222).These findings suggest that excessive cell death may destabilize the barrier and activate immune cells, resulting in additional inflammation