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L.NewhouseS.SordilloP.GrecoK.KarapetisC

(27) noted higher rates of peeling (up to 70%) and burning (up to 45%), along with erythema and PIH, although these were mild, transient, and did not lead to dropouts

Particularly, the MDH enzyme in Thermoleophilum album has maximum activity at pH 7.5 and 60 C, with stability across a wide temperature range (3095 C), though its catalytic activity is limited to a narrow pH range