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These results were particularly striking as long-term responders were immune to rechallenge with the same tumor cells implanted contralaterally in the brain

It was found that the Sonic Hedgehog (SHH) signaling pathway may mediate RA-through mitogen-activated protein kinases/extracellular signal-regulated kinases (MAPK/ERK) signaling pathway by regulate proliferation and migration of FLSs, which are involved in the development of RA

This suggests that mechanisms of UV damage observed in squirrel lenses could be directly applicable to UV cataract formation in humans

PXN LOW also increased BDNF and catalase compared to control (group effect and pairwise comparisons