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(See Figure 4) With this system, the chimeric offspring contain only a minimal genetic modification (the addition of two loxP sites and one Frt site) in the gene of interest, limiting the likelihood of a complicating phenotype

While both may appear the same initially, their symptoms, causes, and treatments differ

This technique is an alternative to traditional spinal fusion surgery, which involves fusing together the vertebrae to stabilize the spine, eliminating motion in the fused segments