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doi: 10.1002/advs.202411813

Zittel TT, Zeeb B, Maier GW, et al

28 The HIFinduced metabolic changes, including enhanced glycolysis, reduced OXPHOS and mitochondrial dysfunction, significantly contribute to the compromised antiviral capabilities of CD8 + T cells during HBV infection

Human safety In blinded clinical trials the overall incidence of adverse events was 2.4 % (similar to placebo) while in open trials the incidence of adverse events was 1 %