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In vitro treatment of high glucose for 72 h resulted in higher ROS accumulation and potentiated TGF pathway activation in PSCs

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Dysfunction of tight junctions is thought to be a primary driver of inflammatory bowel disease and has even been tied to enhanced wheat gluten allergies in celiac disease

Source: FDA Bulk Drug Substances Nominated for Use in Compounding under Section 503A, updated May 14, 2026