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In: UpToDate , Basow, DS (Ed), UpToDate, Waltham, MA

Book a Consultation How It Works IGF-1 LR3 binds directly to IGF-1 receptors on muscle and other tissues, triggering powerful anabolic cascades that promote protein synthesis, cellular growth, and metabolic enhancement with sustained activity

Studies showed that Sermorelin treatment in adults with GHD could increase IGF-1 levels, though not always to the same extent as GH replacement, and produce improvements in body composition (increased lean mass, reduced fat mass), energy levels, exercise capacity, and quality of life measures