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Front Pharmacol 9:1371 Lee N, Carlisle AE, Peppers A, Park SJ, Doshi MB, Spears ME, Kim D (2021) xCT-driven expression of GPX4 determines sensitivity of breast cancer cells to ferroptosis inducers

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PD-L1 draws much attention as an immune checkpoint for improving cancer management [87]

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Regulating lipid production, transportation and decomposition functions with drugs to improve lipid metabolism disorders, especially fatty acid metabolism disorders, and regulating renal energy metabolism can be used as effective methods to prevent and treat RF and delay the progression of CKD [27], which has attracted extensive attention in recent years

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This conjugation process transforms lipophilic toxins into water-soluble glutathione adducts that can be efficiently eliminated through bile or urine

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