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A meta-analysis of 10 randomized controlled trials that included 643 patients with advanced solid tumors using melatonin as the sole therapy or adjuvant therapy reported that melatonin treatment reduced the risk of death at 1 year [54]

For SD-OCT, pupils of both eyes were dilated and 49-section-volume (20 20) high-resolution scans were obtained for each eye with automatic real-time image mean function of 9 or more images and a quality index 20 dB (range, 040 dB)

Nanoparticles offer several advantages over traditional therapies, including improved drug delivery, targeted therapeutic interventions, and crossing biological barriers like the BBB

It also remains unclear how lipid peroxidation products generated during ferroptosis impair myelin-forming capacity of oligodendrocyte precursor cells (OPCs) and worsen white-matter softening, leaving the key drivers of progressive motor dysfunction in PVL insufficiently delineated