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found that the downregulation of the tankyrase PARP reduced cytoplasmic TDP-43 accumulation and potently attenuated neurodegeneration in a Drosophila model 132

Figure 3 MSNs are also widely used for immune therapy and to deliver vaccine into antigen presenting cells (Mody et al., 2013)

It has been reported that buthionine sulfoximine (BSO), a GSH synthesis inhibitor, treatment induced or worsened radiation-related disease and health risk in mice, such as cataracts 16 , brain inflammation 10 , hypertension 17 , atherosclerosis 18 , decreased HDL levels 19 , increased oxidative DNA damage 20 , and tumorigenesis 21

Mutat Res 336 : 917