Vol. XVIII · Free shipping $75+ · Read the collection
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Description

It is well established that during the process of IRI, mitochondrial division increases and fusion decreases, leading to a mitochondrial fissionfusion imbalance ( in vivo and in vitro ( The present study investigated the effects of Hyp during IRI in heart transplantation and explored the mechanism underlying the role of mitochondrial fusion in mediating the cardioprotective effects of Hyp

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Activating transcription factor 4 (ATF4) plays a key role in regulating the expression of Chac1 by directly binding to the ATF4-consensus sequence in the 5 flanking region of the Chac1 gene 28,29,30

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Yen YC, Lin YS, Weng SF, Lai FJ

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Amadori products promote cellular senescence activating insulin-like growth factor-1 receptor and down-regulating the antioxidant enzyme catalase

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