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Historically, the complex action, arousal, autonomic and volitional symptoms of PD were difficult to explain by dysfunction of effector-specific (foot, hand, mouth) motor regions 18

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doi: 10.3390/molecules29040759 Summary Keywords gut-heart axis, heart failure, gut microbiota metabolites, mechanism of action, intervention measures Citation Guo S, Zhang W, Cui X and Yin B (2025) The bidirectional regulatory mechanism of gut microbiota metabolites on myocardial injury in heart failure from the perspective of the gut-heart axis: a review

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