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In CKD patients, uremic retention solutes such as guanidine, p -cresol, indoxyl sulfate, and asymmetric dimethylarginine (ADMA) have been suggested to have proatherogenic properties [58]

Yu H, Yang C, Jian L, Guo S, Chen R, Li K, et al

Zachoval et al

Clinical trials of BI 425809 have yielded encouraging results in phase I and phase II studies, reinforcing its potential cognitive benefits in schizophrenia (Moschetti et al