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Description

The mechanistic difference translates directly to side-effect profiles: cagrilintide causes nausea and vomiting in 3040% of subjects during dose titration (similar to GLP-1 agonists), while tesofensine produces insomnia, dry mouth, and increased heart rate in 2035% due to its sympathomimetic effects

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A large number of patients lose a few percent of body weight over a period of months, enough in some cases to restore ovulation

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