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Using a mouse model, we identified the key factor through which NRTP damages ovaries and then designed targeted therapies to protect ovaries in a mouse model, thereby providing novel strategies for the future clinical application of targeted protection of ovaries from NRTP-induced damage

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Graphical Abstract Similar content being viewed by others Introduction The tight junction-connected, non-fenestrated brain capillary endothelial cells in cross-talk with the neighboring pericytes and astroglial endfeet create the dynamic anatomical and functional unit called as bloodbrain barrier (BBB) [1]