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A scaled sliding template method (AxoGraph X) was used to detect spontaneous EPSCs

Abbreviations BBB: Blood-brain barrier BER: Berberine CS: Chitosan DMSO: Dimethyl sulfoxide EE %: Percentage entrapment efficiency GFAB: Glial fibrillary acid protein GSH: Reduced glutathione IHC: Immunohistochemistry MAO-B: Monoamine oxidase B MPTP/P: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine PDI: Polydispersity index PD: Parkinsons disease SOD: Superoxide dismutase TEM: Transmission electron microscopy TNF-: Tumor necrosis factor alpha References Cheng Z, Kang C, Che S, Su J, Sun Q, Ge T, Guo Y, Lv J, Sun Z, Yang W, Li B, Li X, Cui R

Quantification of GSH using LCMS Cells were incubated with 100 M of N -methyl maleimide (NMM) in PBS for 15 min at room temperature to derivatize all the small-molecule thiols

Free radicals are also called reactive oxygen species (ROS)