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This review delves into the critical role of SIRT3, a key mitochondrial deacetylase, in regulating mitochondrial bioenergetics, oxidative stress, and neuroinflammationcentral mechanisms underlying peripheral neuropathy and neuropathic pain

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doi: 10.3390/jof8111121 11 ArastehfarA.DaneshniaF.CabreraN.Penalva-LopezS.SarathyJ.ZimmermanM.et al

The peptide exhibits anabolic and metabolic activities through IGF-1 receptor binding, though it has never been approved for therapeutic human use and remains confined to research applications [12]