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One was a clinical study.[4] That one clinical study was a retrospective case series reporting that 7 of 12 patients experienced pain relief lasting more than six months following intra-articular knee injections for chronic knee pain

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In addition to facilitating the release of synaptic vesicles, Shimojo and colleagues [106] demonstrated that syb2, SNAP25, and SNAP47 facilitate BDNF release in cortical neurons