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As GSH represent the primary antioxidant defense system, the reduction of GSH could influence the redox homeostasis and elevate the naturally occurring ROS levels inside the cancer cells 40

Characteristic 5: Absence of Chronic Hyperinsulinemia Elevated fasting insulin, as seen in metabolic syndrome, increases somatostatin tone through mechanisms partly mediated by IGF-1 feedback

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While consuming a diet rich in Glutathione or taking supplements can increase the levels of Glutathione in the body, the efficacy of this antioxidant diminishes as it passes through the digestive system