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Paeonol ameliorates hippocampal neuronal damage by inhibiting GRM5/GABBR2/-arrestin2 and activating the cAMP-PKA signaling pathway in premenstrual irritability rats

Increasing drug sensitivity The increased expression of hypoxia-inducible factor-1 (HIF-1) in TME facilitates the adaptation of tumor cells to hypoxia [162, 163]