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Endocrinology , 142 (12), 5182-5189

Melatonin is important for improving mitochondrial function, reducing free radical damage, and inducing oocyte maturation, which can improve the fertilization rate, promote embryo development, and positively affect in vitro fertilization and embryo transfer

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Male and female Balb/c mice or Balb/c nude mice (78 weeks old) were purchased from Vital River Laboratory Animal Technology (Beijing, China) and Shanghai Model Organisms Center, Inc