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In the slightly acidic TME, six-transmembrane epithelial antigen of prostate 3 (STEAP3) reduces Fe3 to Fe2, which is then transported into the cytoplasmic LIP via divalent metal transporter 1 (DMT1) (Torti and Torti 2013)

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Analysis of splenic sections showed CD5/ LNP mainly colocalized with T cells (CD3e positive) and rarely colocalized with B cells (CD19) or DCs (CD11c)

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