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Direct answer: Patients most often ask about safety, duration, weight regain, and risks after several years

Nature 570 , 7176 (2019)

[133] reported a randomized, controlled, single-blind, intra-patient left- to right-side trial comparing the efficacy and safety of vitamin B 12 -containing ointment (0.07% cyanocobalamin in a w/o formulation with 20% avocado oil) (M-treatment) with a glycerol-petrolatum-based emollient cream (C-treatment) in 24 patients with mild-to-moderate plaque psoriasis for a period over 12 weeks followed by a wash-out observation period of 4 weeks

Pharmaceutical Development: It is explored for its potential in drug formulations aimed at enhancing blood flow and treating conditions related to vascular health, offering a targeted approach compared to traditional treatments