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To provide an example of the FDAs denial of adverse health effects of amalgam, the FDA states In addition, the estimated concentration of mercury in breast milk attributable to dental amalgam is an order of magnitude below the EPA protective reference dose for oral exposure to inorganic mercury

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In antidote administration, most subjects would receive only one dose, or at most a few doses over a short period of time, and these chronic and subacute animal studies would not seem to be particularly relevant

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