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We performed a systematic, parallelised comparison of NERNST responses with the NAPstarC, NAPstar3 and NAPstar6 sensors, as well as roGFP2 and roGFP2-Grx1, in WT, glr1 , grx1 grx2 and glr1 grx1 grx2 yeast cells, with H 2 O 2, diamide and t -BuOOH as three different oxidants (Supplementary Figs

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doi: 10.1038/nature17412 285 LiWTanikawaTKryczekIXiaHLiGWuKet al

[12:42] If you add to that that the microglia also influence quinolinic acid, serotonin, dopamine, and a host of other neurochemical pathways that then influence the neuroexcitatory sympathetic response, you've got sensory overwhelm, everything in the world seems disproportionately threatening, and you're hyper-alert