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In AD patients, GLUT1 expression is often reduced in the hippocampus and frontal cortex, 270,271,272 which may limit glucose entry and affect cellular energy supply

Strict sense dehydration refers to water loss alone

because these models recapitulate the essential pathological and biochemical trademarks of PD including oxidative stress, mitochondrial dysfunction and DA degeneration

Investigations with animal model induced to intense and exhaustive aerobic exercise protocols or, in situations of high catabolism, such as sepsis, show that chronic supplementation with DIP or with glutamine and alanine in their free forms is efficient for the supply of glutamine to the body, which can attenuate biomarkers of injury and inflammation after periods of intense training, as well as attenuate the inflammatory response induced by long-term exercise [142]