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Understanding the metabolism of APAP and its potential for toxicity is crucial for timely diagnosis and effective treatment of overdose cases

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Cellular localization then determines the source of ROS/RNS/RSS and their proximity to potential cysteine modifications, type of antioxidant defense, and the redox potential of cysteine residues present

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They may become useful around transplant optimisation, but they need more independent evidence before being positioned as routine treatment

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