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In: Medical Oncology: A Comprehensive Review

At the moment of full synthesis of the recombinant protein, depletion of low-abundance tRNAs occurs

390 NOX activation NOX activation drives ROS generation in cancer therapy, exemplified by ZIO-101 (Darinaparsin), which induces NOX-mediated ROS production and mitochondrial disruption, triggering apoptosis in hematologic and solid tumors