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ML: Methodology, Supervision

10.3390/ijms22179600 Int

20 M paeonol increased the enzymatic activities of SOD, CAT, GSH-Px and the expression of HO-1, NQO1, and SOD2 by activating the Nrf2 signaling pathway, but paeonol was unable to affect melanogenesis in PIG1 cells and acted only as a protective agent (Guo and Zhang 2021)