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These results are consistent with the major features of hind-limb suspension-related phenotypes of skeletal muscles as an index of anti-gravity muscle atrophy 66 , thus assuring that the experimental design including the mouse age and muscle-disuse period (in vivo assay time-point) were appropriate to the conclusion that 3-days LASSS oral-administration prevents tyrosine-residue nitration of extracellular HGF (Y198) during 5-days muscle disuse

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Among these genes, only GGCT expression was significantly elevated in tumor tissues compared to normal tissues both in HCC and PCa, whereas other genes (GCLC, GCLM, GGT1, and others) showed no significant increase (Fig