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Once an antioxidant has deactivated a free radical, the damaging process is stopped in its tracks, but the antioxidant wont be able to neutralise any further free radicals

10.1016/j.celrep.2016.04.006

J Natl Compr Canc Netw 15(3):411-419, 2017

59,60 Specific genes implicated include vascular endothelial growth factor (VEGF), neurotrophic receptor tyrosine kinase 1, sodium voltage-gated channel alpha subunit 2 (SCN2A), angiotensin-converting enzyme, and methylenetetrahydrofolate reductase, with polymorphisms associated with increased DN susceptibility