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Abe and Kimura, 2 S levels in the plasma of AD patients, which correlated with the degree of cognitive decline (Liu et al., 142 into the hippocampi of rats induced cognitive impairment and reduction in H 2 S levels and expression of endogenous CBS and 3-MST and intraperitoneal injection of the H 2 S donor, NaSH, ameliorated cognitive deficits as well as neuroinflammation (Liu et al., 2 S in mouse models of AD, although the effects of sulfhydration on signaling pathways were not evaluated (Giuliani et al., 2016

Interestingly, in another study it was suggested that lamina propria Treg cells showed increased rate of apoptosis suggesting impaired immunosuppressive role of Treg cells in chronic IBD (177)

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