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We next investigated hepatic GSH metabolism as GSH plays an important role in acrolein detoxification [29,33] as well as regulation of tissue redox homeostasis [16]

Curcumin mitigates neuronal degeneration by blocking the histone deacetylase 6 (HDAC6)-NLRP3 signaling pathway to suppress NLRP3 inflammasome-mediated inflammatory responses and counteracts -syn-induced neurotoxicity (Liu et al., 2011)