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Maintaining current vision longer before significant decline

Randomized, placebo-controlled comparison of amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and quality of life

The sustained tonic GH/IGF-1 elevation it produces rather than pulsatile bursts is both a research advantage (easier to measure steady-state changes in body composition) and a design consideration (it does not replicate physiological GH pulsatility, which may matter in neuroendocrine studies)