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Peana M, Pelucelli A, Medici S, Cappai R, Nurchi VM, Zoroddu MA

Regulation of thiol-disuphide status has traditionally been associated with TRX (Buchanan & Balmer 2005).However, genetic support for the physiological importance of glutathione-dependent disulphide reduction comes from the observations that the NADPH-TRX and glutathione systems play overlapping roles in development (Reichheld et al

In I/R research, experimental models have provided considerable advances in understanding its mechanisms, as well as in testing new strategies to reduce tissue damage