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UCHL1 is also essential for normal structure and function of neuromuscular junctions (NMJs), reduction of synaptic vesicles and accumulation of tubulovesicular structures at the presynaptic nerve terminals have been observed in Uchl1 knockout mice (Chen et al., 2010)

Barreiro E, de la Puente B, Busquets S, Lopez-Soriano FJ, Gea J, Argiles JM

The pulmonary tissue structure of mice exposed to hyperoxia becomes disordered, the alveolar wall begins to weaken as the hyperoxia exposure period increases, and the concentration of antioxidative stress-related enzymes (CAT, SOD, and GSH-Px) decreases under hypoxia condition

In 2021, the American Academy of Dermatology joined with the National Psoriasis Foundation to issue new guidance on the suggested treatment of psoriasis