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10.1038/nature05859 170 YangJ.WangC.ChengS.ZhangY.JinY.ZhangN.et al (2023)

Furthermore, DNA methylation studies identified DMRs in glaucoma-related genes, such as PLEKHA7 and PITX2 , between primary open-angle glaucoma (POAG) patients and normal Schlemms canal cells (Fraga and Esteller, 2007), reinforcing the link between methylation and glaucoma pathology